CyberSecBulletin
CVE-2026-24216NVD status: Analyzed

BioNeMo Framework: Deserialization of Untrusted Data

CVE-2026-24216 is a high-severity deserialization of untrusted data vulnerability in BioNeMo Framework from NVIDIA, with a CVSS 3.1 base score of 7.8 out of 10. It can be exploited with local access to the system by an unauthenticated attacker, but only if a user takes part, for example by opening a link or file. The record lists version commit dfd83a7 in Main as the first without the flaw, so updating BioNeMo Framework to that release or later removes the exposure. There is no confirmed exploitation so far. EPSS estimates a 0.29% chance of exploitation within 30 days, which is low compared with other CVEs.

Next patch cycle

High severity with no evidence of exploitation so far.

What to do

  1. Update BioNeMo Framework to commit dfd83a7 in Main or a later version.
  2. Read the advisory on nvidia.custhelp.com for workarounds and exact fixed builds.
  3. Because the attack needs a user to take part, warn users about unexpected links and files related to this product until it is patched.

Affected products and versions

VendorProductAffected versionsFixed in
NVIDIABioNeMo Frameworkbefore commit dfd83a7 in Maincommit dfd83a7 in Main

Version data comes from the organisation that assigned the CVE. Confirm against the vendor advisory before deciding you are unaffected.

How the severity score breaks down

Attack vector
LocalThe attacker needs local access or must trick a user into running something.
Attack complexity
LowNo special conditions are needed; the attack works reliably.
Privileges required
NoneNo account or login is needed.
User interaction
RequiredA user must take an action such as opening a file or link.
Scope
UnchangedImpact stays within the vulnerable component.
Confidentiality
HighAll data handled by the component can be read.
Integrity
HighData or code can be modified at will.
Availability
HighThe component can be taken down completely.

Vector: CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H. Scored by CNA (nvidia.com).

Official description

NVIDIA BioNemo for Linux contains a vulnerability where a user could cause a deserialization of untrusted data. A successful exploit of this vulnerability might lead to code execution, denial of service, information disclosure, and data tampering.

Source: the CVE record as published by its numbering authority, via NVD and CVE.org.

The underlying weakness: Deserialization of Untrusted Data

The product deserializes untrusted data without sufficiently ensuring that the resulting data will be valid.

How developers prevent this class of flaw

  • If available, use the signing/sealing features of the programming language to assure that deserialized data has not been tainted. For example, a hash-based message authentication code (HMAC) could be used to ensure that data has not been modified.
  • When deserializing data, populate a new object rather than just deserializing. The result is that the data flows through safe input validation and that the functions are safe.
  • Explicitly define a final object() to prevent deserialization.

More Deserialization of Untrusted Data vulnerabilities (CWE-502)

Timeline

  1. CVE record published.
  2. CISA published its SSVC assessment (exploitation: none, automatable: no, technical impact: total).
  3. Record last changed materially (score, affected products, status or references).

References

Third-party and government advisories

Other vulnerabilities in BioNeMo Framework

All BioNeMo Framework vulnerabilities

Recent Deserialization of Untrusted Data vulnerabilities

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